Theranostics publishes innovative research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image-guided therapy, biosensors, system biology and translational medicine, personalized medicine and a broad spectrum of biomedical research that can be applied to future theranostic applications.

Research Paper
HDAC6 inhibition reverses long-term doxorubicin-induced cognitive dysfunction by restoring microglia homeostasis and synaptic integrity
Blake R McAlpin, Rajasekaran Mahalingam, Anand K Singh, Shruti Dharmaraj, Taylor T Chrisikos, Nabila Boukelmoune, Annemieke Kavelaars, Cobi J Heijnen
Theranostics 2022; 12(2): 603-619. doi:10.7150/thno.67410
[Abstract] [Full text] [PDF]

Review
Tailoring noble metal nanoparticle designs to enable sensitive lateral flow immunoassay
Xirui Chen, Lu Ding, Xiaolin Huang, Yonghua Xiong
Theranostics 2022; 12(2): 574-602. doi:10.7150/thno.67184
[Abstract] [Full text] [PDF]

Research Paper
Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds
Yu-Hang Liu, Lorenz M. Brunner, Johannes Rebling, Maya Ben-Yehuda Greenwald, Sabine Werner, Michael Detmar, Daniel Razansky
Theranostics 2022; 12(2): 558-573. doi:10.7150/thno.65287
[Abstract] [Full text] [PDF]

Review
Light on osteoarthritic joint: from bench to bed
Yingying Zhou, Junguo Ni, Chunyi Wen, Puxiang Lai
Theranostics 2022; 12(2): 542-557. doi:10.7150/thno.64340
[Abstract] [Full text] [PDF]

Research Paper
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice
Xiangyu Zhang, Hui Liu, Jennifer Q Zhou, Stefanie Krick, Jarrod W Barnes, Victor J Thannickal, Yan Y Sanders
Theranostics 2022; 12(2): 530-541. doi:10.7150/thno.62760
[Abstract] [Full text] [PDF]

Research Paper
Monocytes promote acute neuroinflammation and become pathological microglia in neonatal hypoxic-ischemic brain injury
Hong-Ru Chen, Ching-Wen Chen, Yi-Min Kuo, Brandon Chen, Irena S. Kuan, Henry Huang, Jolly Lee, Neil Anthony, Chia-Yi Kuan, Yu-Yo Sun
Theranostics 2022; 12(2): 512-529. doi:10.7150/thno.64033
[Abstract] [Full text] [PDF]

Review
Glucose biosensors in clinical practice: principles, limits and perspectives of currently used devices
Salvatore Andrea Pullano, Marta Greco, Maria Giovanna Bianco, Daniela Foti, Antonio Brunetti, Antonino S. Fiorillo
Theranostics 2022; 12(2): 493-511. doi:10.7150/thno.64035
[Abstract] [Full text] [PDF]

Research Paper
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy
Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot
Theranostics 2022; 12(2): 474-492. doi:10.7150/thno.63744
[Abstract] [Full text] [PDF]

Research Paper
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype
Sheng-Qing Lv, Zhen Fu, Lin Yang, Qing-Rui Li, Jiang Zhu, Qu-Jing Gai, Min Mao, Jiang He, Yan Qin, Xiao-Xue Yao, Xi Lan, Yan-Xia Wang, Hui-Min Lu, Yan Xiang, Zuo-Xin Zhang, Guo-Hao Huang, Wei Yang, Ping Kang, Zhijian Sun, Yu Shi, Xiao-Hong Yao, Xiu-Wu Bian, Yan Wang
Theranostics 2022; 12(1): 459-473. doi:10.7150/thno.65739
[Abstract] [Full text] [PDF]

Review
Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy
Bin Ji, Minjie Wei, Bin Yang
Theranostics 2022; 12(1): 434-458. doi:10.7150/thno.67300
[Abstract] [Full text] [PDF]

Research Paper
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics
Xuejun Wen, Pengfei Xu, Mengqi Shi, Jia Liu, Xinying Zeng, Yiren Zhang, Changrong Shi, Jingchao Li, Zhide Guo, Xianzhong Zhang, Pek-Lan Khong, Xiaoyuan Chen
Theranostics 2022; 12(1): 422-433. doi:10.7150/thno.68182
[Abstract] [Full text] [PDF]

Erratum
Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis: Erratum
Haoran Liu, Xiaoqi Yang, Kun Tang, Tao Ye, Chen Duan, Peng Lv, Libin Yan, Xiaoliang Wu, Zhiqiang Chen, Jianhe Liu, Yaoliang Deng, Guohua Zeng, Jinchun Xing, Zhangqun Ye, Hua Xu
Theranostics 2022; 12(1): 421. doi:10.7150/thno.68830
[Abstract] [Full text] [PDF]

Erratum
Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma: Erratum
Libin Yan, Beichen Ding, Haoran Liu, Yangjun Zhang, Jin Zeng, Junhui Hu, Weimin Yao, Gan Yu, Ruihua An, Zhiqiang Chen, Zhangqun Ye, Jinchun Xing, Kefeng Xiao, Lily Wu, Hua Xu
Theranostics 2022; 12(1): 419-420. doi:10.7150/thno.68810
[Abstract] [Full text] [PDF]

Erratum
NLRP3 inflammasome via IL-1β regulates PCSK9 secretion: Erratum
Zufeng Ding, Xianwei Wang, Shijie Liu, Sichang Zhou, Rajshekhar A Kore, Shengyu Mu, Xiaoyan Deng, Yubo Fan, Jawahar L Mehta
Theranostics 2022; 12(1): 418. doi:10.7150/thno.68759
[Abstract] [Full text] [PDF]

Research Paper
Simultaneous enhancement of T₁ and T₂ magnetic resonance imaging of liver tumor at respective low and high magnetic fields
Huan Li, Zijuan Hai, Liwei Zou, Lele Zhang, Lulu Wang, Longsheng Wang, Gaolin Liang
Theranostics 2022; 12(1): 410-417. doi:10.7150/thno.67155
[Abstract] [Full text] [PDF]

Research Paper
A hypoxia-responsive supramolecular formulation for imaging-guided photothermal therapy
Tian-Xing Zhang, Xiaoxue Hou, Yong Kong, Fan Yang, Yu-Xin Yue, Muhammad Raza Shah, Hua-Bin Li, Fan Huang, Jianfeng Liu, Dong-Sheng Guo
Theranostics 2022; 12(1): 396-409. doi:10.7150/thno.67036
[Abstract] [Full text] [PDF]

More ...