Jul 13, 2026

RefSeq release 236 is now available online and from the FTP site! You can access RefSeq data through NCBI Datasets. The release is provided in several directories as a complete dataset and also as divided by logical groupings.     What’s included in this release?   As of July 6, 2026, this full release incorporates genomic, transcript, and protein data containing:    629,953,391 records   482,864,455 proteins   83,806,434 RNAs   Sequences from 182,465 organisms   New eukaryotic … Continue reading Now Available: RefSeq Release 236 →

Jul 1, 2026

Download release 20.0 of the NCBI protein profile Hidden Markov models (HMMs) used by the Prokaryotic Genome Annotation Pipeline (PGAP). You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package.    What’s new?    Release 20.0 contains:    18,950 HMMs maintained by NCBI    497 new HMMs since release 19.0    You can search and view the … Continue reading Now Available! NCBI Hidden Markov Models (HMM) Release 20.0 →

Jun 29, 2026

What you need to know for 2026 and beyond!  The volume of genomic sequencing data is growing rapidly, and we want to ensure that publicly shared datasets remain useful, findable, and scientifically trustworthy. To support this goal, the Sequence Read Archive (SRA) is implementing a set of data submission standards that improve data consistency, quality, and long-term value—benefiting both the … Continue reading Standards for Sequence Read Archive (SRA) Data Submission →