{"id":224244,"date":"2025-08-08T20:24:38","date_gmt":"2025-08-08T20:24:38","guid":{"rendered":"https:\/\/avitastaging.wpenginepowered.com\/?page_id=1452"},"modified":"2026-03-19T16:57:49","modified_gmt":"2026-03-19T16:57:49","slug":"published-evidence","status":"publish","type":"page","link":"https:\/\/avitamedical.com\/published-evidence\/","title":{"rendered":"Published Evidence"},"content":{"rendered":"

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RESEARCH<\/h4>\n

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RESEARCH<\/h4>\n

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RESEARCH<\/h4>\n

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Published Evidence<\/h1>\n

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Published Evidence<\/h1>\n

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Published Evidence<\/h1>\n

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RESEARCH<\/h4>\n

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RESEARCH<\/h4>\n

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RESEARCH<\/h4>\n

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Published Evidence<\/h1>\n

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Published Evidence<\/h1>\n

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Published Evidence<\/h1>\n

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Explore the Science Driving Innovation in Wound Healing<\/p>\n

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At AVITA Medical, science is central to everything we do. Our portfolio is built on a foundation of peer-reviewed research and real-world clinical experience. We are advancing evidence that supports better care in skin restoration, from well-established research supporting RECELL\u00ae<\/span> to emerging clinical data around our next-generation disruptive technologies.<\/p>\n

For inquires about our published evidence, please contact the AVITA Medical customer service team at 833-462-8482<\/a>, or complete our contact<\/a> us form.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

[\/et_pb_text][et_pb_image src=”https:\/\/avitamedical.com\/wp-content\/uploads\/2026\/03\/Portfolio-Evidence-Landscape-03.16.26-scaled.jpg” alt=”AVITA Portfolio Publications by Study Design” title_text=”Portfolio Evidence Landscape 03.16.26″ align=”center” _builder_version=”4.22.1″ _module_preset=”default” width=”80%” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.22.1″ _module_preset=”default” text_text_color=”gcid-body-color” global_colors_info=”{%22gcid-body-color%22:%91%22text_text_color%22%93}”]<\/p>\n

Chart updated: March 2026<\/p>\n

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Key Peer-Reviewed Publications<\/p>\n

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Title<\/strong><\/h4>\n<\/td>\n

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Authors (Journal<\/em>, Year)<\/strong><\/h4>\n<\/td>\n

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Study Design<\/strong><\/h4>\n<\/td>\n

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Indication<\/strong><\/h4>\n<\/td>\n

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Summary of Evidence<\/strong><\/h4>\n<\/td>\n<\/tr>\n

Maximizing wound coverage in full-thickness skin defects: A randomized-controlled trial of autologous skin cell suspension and widely meshed autograft versus standard autografting<\/td>\nHenry et al. (J Trauma Acute Care <\/em>Surg., 2024)<\/td>\nExperimental (Randomized Controlled Trial)<\/td>\nSurgical & traumatic wounds<\/td>\n\n

In patients with nonthermal full-thickness wounds, treatment with RECELL plus widely meshed autograft significantly reduced donor skin requirements by 27% compared to less widely meshed autografting.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n

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Demonstration of the safety and effectiveness of the RECELL\u00ae<\/sup> System combined with split-thickness meshed autografts for the reduction of donor skin to treat mixed-depth burn injuries<\/p>\n

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Holmes et al. (Burns, 2019)<\/td>\nExperimental (Randomized Controlled Trial)<\/td>\nBurns<\/td>\n\n

In patients with mixed-depth burns (inclusive of full-thickness), treatment with RECELL plus widely meshed autograft significantly reduced donor skin requirements by 32% compared to less widely meshed autografting.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

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A comparative study of the RECELL Device and autologous split-thickness meshed skin graft in the treatment of acute burn injuries<\/p>\n

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Holmes et al. (J Burn Care Res.<\/em>, 2018)<\/td>\nExperimental (Randomized Controlled Trial)<\/td>\nBurns<\/td>\n\n

In patients with deep partial-thickness burns, treatment with RECELL alone significantly reduced donor skin requirements by 97.5% compared to 2:1 meshed autografting. The RECELL donor site resulted in significantly less pain, faster healing, and improved patient satisfaction.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n

A comparative study of spray keratinocytes and autologous meshed split-thickness skin graft in the treatment of acute burn injuries<\/td>\nSood et al. (Wounds<\/em>, 2015)<\/td>\nExperimental (Randomized Controlled Trial)<\/td>\nBurns<\/td>\nIn patients with partial-thickness burns, treatment with RECELL alone resulted in decreased donor size and comparable healing outcomes compared to meshed autografting alone. Read it here<\/a><\/span><\/td>\n<\/tr>\n
Analysis of real-world length of stay data and costs associated with use of autologous skin cell suspension for the treatment of small burns in U.S. centers<\/td>\nCarson et al. (Burns<\/em>, 2023)<\/td>\nObservational<\/td>\nBurns<\/td>\n\n

Use of RECELL for small burns (<20% TBSA) in U.S. centers was associated with an average 2.1 day reduction in length of stay, translating to a $22,268 cost savings per patient.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

Length of stay and costs with autologous skin cell suspension versus split-thickness skin grafts: Burn care data from US centers<\/td>\nCarter et al. (Adv Ther.<\/em>, 2022)<\/td>\nObservational<\/td>\nBurns<\/td>\n\n

Use of RECELL for burns up to 50% TBSA in U.S. centers was associated with an average 3.3 day reduction in length of stay, translating to a $36,949 cost savings per patient.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

Cost-effectiveness of the use of autologous cell harvesting device compared to standard of care for treatment of severe burns in the United States<\/td>\n\n

Kowal et al. (Adv Ther.<\/em>, 2019)<\/p>\n

 <\/p>\n<\/td>\n

Foundational Research<\/td>\nBurns<\/td>\n\n

Economic models demonstrate that hospital length of stay accounts for up to 70% of cost reductions, with estimated per-patient savings ranging from $31,000 to over $150,000, and projected annual savings of $5.3 to $6.8 million for a representative U.S. burn center treating 200 patients.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n

Autologous skin cell suspension for full-thickness skin defect reconstruction: Current evidence and health economic expectations<\/td>\nKahn et al. (Adv Ther.<\/em>, 2024)<\/td>\nNarrative Review<\/td>\nSurgical & traumatic wounds<\/td>\n\n

This article discusses the cost benefits that may be anticipated with the use of RECELL for surgical & traumatic full-thickness wounds.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

Biological attributes required for epidermal regeneration: Evaluation of the next-generation autologous cell harvesting device<\/td>\nBush et al. (Int Wound J.<\/em>, 2024)<\/td>\nFoundational Research<\/td>\n–<\/td>\n\n

The RECELL GO device aids in the preparation of a comparable skin cell suspension to the previous device with improved standardization and reduced variability in cell count.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n

Wound healing and scar patterning after addition of autologous skin cell suspension to meshed grafts<\/td>\nCollins et al. (J Surg Res.<\/em>, 2024)<\/td>\nFoundational Research<\/td>\nSurgical wounds<\/td>\n\n

In porcine full-thickness wounds treated with 3:1 meshed autograft, the addition of RECELL significantly increased rate of re-epithelialization of interstices at early time points.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

Sprayed keratinocyte suspensions accelerate epidermal coverage in a porcine microwound model<\/td>\nNavarro et al. (J Burn Care Rehabil.<\/em>, 2000)<\/td>\nFoundational Research<\/td>\nSurgical wounds<\/td>\n\n

In porcine full-thickness wounds treated with 3:1 meshed autograft, the addition of RECELL resulted in faster and better quality of epithelialization at the cellular level.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/dipi_advanced_tabs_item][dipi_advanced_tabs_item title=” PermeaDerm” img_container_max_width=”100vw” tab_media=”none” _builder_version=”4.27.4″ _module_preset=”default” title_text_align=”center” text_font_size=”1rem” link_text_color=”#4d7bc4″ link_font_size=”1rem” width_tablet=”” width_phone=”96%” width_last_edited=”on|phone” module_alignment=”left” title_font_size_tablet=”” title_font_size_phone=”” title_font_size_last_edited=”on|phone” title_line_height_tablet=”” title_line_height_phone=”1.8em” title_line_height_last_edited=”on|phone” header_5_line_height_tablet=”” header_5_line_height_phone=”1.3em” header_5_line_height_last_edited=”on|phone” global_colors_info=”{}” custom_css_main_element_last_edited=”on|phone” custom_css_main_element_phone=”margin-left:1vw;||margin-right:1vw;”]<\/p>\n\n\n\n\n\n\n\n\n\n\n
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Title<\/strong><\/h4>\n<\/td>\n

\n

Authors (Journal<\/em>, Year)<\/strong><\/h4>\n<\/td>\n

\n

Study Design <\/strong><\/h4>\n<\/td>\n

\n

Indication<\/strong><\/h4>\n<\/td>\n

\n

Summary of Evidence<\/strong><\/h4>\n<\/td>\n<\/tr>\n

A randomized, controlled trial comparing PermeaDerm\u00ae <\/sup>to Mepilex Ag\u00ae<\/sup> in the treatment of adult and pediatric partial-thickness burns<\/td>\nGreenhalgh et al. (J Burn Care Res.<\/em>, 2025)<\/td>\nExperimental (Randomized Controlled Trial)<\/td>\nBurns<\/td>\n\n

In (mostly pediatric) patients with partial-thickness burns, treatment with PermeaDerm significantly reduced the odds of needing a dressing change compared to Mepilex Ag.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n

Initial experience using a biosynthetic wound matrix for full-thickness wound temporization<\/td>\nAkpunonu et al. (J Surg.<\/em>, 2025)<\/td>\nObservational<\/td>\nSurgical wounds<\/td>\n\n

PermeaDerm performed as a viable option for temporizing full-thickness wounds, The authors concluded that PermeaDerm is an effective alternative to allograft, delivering similar clinical outcomes while offering advantages like simplified storage, reduced cost, easier application, and optimized management.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

Use of a bioactive matrix glove in the treatment of pediatric hand burns: a case series<\/td>\nJulian et al. (J Wound Care<\/em>, 2024).<\/td>\nObservational<\/td>\nBurns<\/td>\n\n

In pediatric patients with partial-thickness hand burns, the PermeaDerm glove resulted in successful healing with minimal scarring, preserved joint mobility, and minimal need for dressing changes.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n

Preliminary study of wound oxygenation comparing skin substitutes and dressings<\/td>\nWoodroof et al. (Eplasty<\/em>, 2023)<\/td>\nFoundational Research<\/td>\n–<\/td>\n\n

PermeaDerm transferred oxygen significantly faster than Integra\u00ae<\/sup> Dermal Regeneration Template and NovoSorb\u2122 Biodegradable Temporizing Matrix, suggesting its potential to enhance wound healing by improving oxygenation delivery.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

In vitro characterization of variable porosity wound dressing with anti-scar properties<\/td>\nWoeller et al. (Eplasty<\/em>, 2018)<\/td>\nFoundational Research<\/td>\n–<\/td>\n\n

PermeaDerm supported cell growth and reduced scar-associated myofibroblast formation and inflammatory cytokines.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n

Evaluating a variable porosity wound dressing with anti-scar properties in a porcine model of wound healing<\/td>\nWoeller et al. (Eplasty<\/em>, 2018)<\/td>\nFoundational Research<\/td>\nSurgical wounds<\/td>\n\n

In full-thickness porcine wounds, those treated with PermeaDerm healed more effectively and showed potential to reduce excessive scar formation compared to those not treated.<\/p>\n

Read it here<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

Evolution of a temporary biosynthetic skin substitute: A preliminary study<\/td>\nWoodroof et al. (Eplasty<\/em>, 2015)<\/td>\nFoundational Research<\/td>\nSurgical wounds<\/td>\n\n

PermeaDerm demonstrated better control of inflammation, reduced scarring markers, and superior cell growth and migration compared to Biobrane\u00ae<\/sup>.<\/p>\n

Read it here<\/a><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

[\/dipi_advanced_tabs_item][dipi_advanced_tabs_item title=”Cohealyx” img_container_max_width=”26vw” tab_media=”none” _builder_version=”4.22.1″ _module_preset=”default” title_text_align=”center” text_font_size=”1rem” link_text_color=”#4d7bc4″ link_font_size=”1rem” header_5_line_height=”1.3em” width_tablet=”” width_phone=”96%” width_last_edited=”on|phone” hover_enabled=”0″ title_font_size_tablet=”” title_font_size_phone=”” title_font_size_last_edited=”on|phone” header_5_line_height_tablet=”1.3em” header_5_line_height_phone=”1.3rem” header_5_line_height_last_edited=”on|phone” module_alignment_tablet=”” module_alignment_phone=”left” module_alignment_last_edited=”on|phone” global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n\n\n\n\n\n\n
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Title<\/strong><\/h4>\n<\/td>\n

\n

Authors (Journal<\/em>, Year)<\/strong><\/h4>\n<\/td>\n

\n

Study Design <\/strong><\/h4>\n

\u00a0<\/strong><\/h4>\n<\/td>\n

\n

Indication<\/strong><\/h4>\n<\/td>\n

\n

Summary of Evidence<\/strong><\/h4>\n<\/td>\n<\/tr>\n

Bovine Dermal Collagen Matrix for Early Graft Readiness in a Full-Thickness Posterior Neck Burn: A Case Report<\/td>\nGibson et al. (Cereus<\/em>\u00a02025)<\/td>\nObservational<\/td>\nSurgical wounds<\/td>\nCohealyx supported graft readiness of a full-thickness neck injury in 12 days, demonstrating its clinical potential to support definitive closure with excellent clinical performance and conformability in complex anatomical locations.<\/p>\n

Read it here<\/a><\/td>\n<\/tr>\n

A bovine dermal collagen matrix (BDCM) advances readiness to autografting: A case series<\/td>\nAkpunonu et al. (J Surg.<\/em>, 2025)<\/td>\nObservational<\/td>\nSurgical wounds<\/td>\nCohealyx supported wound bed vascularization within 5-10 days, demonstrating its clinical potential as a dermal matrix option to support timely graft-readiness.<\/p>\n

Read it here<\/a><\/td>\n<\/tr>\n

Bovine dermal collagen matrix promotes vascularized tissue generation supporting early definitive closure in full-thickness wounds: A pre-clinical study<\/td>\nBush et al. (Cureus<\/em>, 2025)<\/td>\nFoundational Research<\/td>\nSurgical wounds<\/td>\nIn full-thickness porcine wounds, Cohealyx supported rapid cellular infiltration and vascularized tissue formation, supporting autograft readiness at Day 7 and earlier definitive closure compared to Integra\u00ae<\/sup> Bilayer Wound Matrix and Kerecis\u00ae<\/sup>.<\/p>\n

Read it here<\/a><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Discover RECELL\u00ae through abstracts, videos, and publications that support efficacy in diverse applications, from burns to full-thickness skin defects and beyond.<\/p>\n","protected":false},"author":2,"featured_media":224273,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"dipi_cpt_category":[],"class_list":["post-224244","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/pages\/224244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/comments?post=224244"}],"version-history":[{"count":0,"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/pages\/224244\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/media\/224273"}],"wp:attachment":[{"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/media?parent=224244"}],"wp:term":[{"taxonomy":"dipi_cpt_category","embeddable":true,"href":"https:\/\/avitamedical.com\/wp-json\/wp\/v2\/dipi_cpt_category?post=224244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}