✕
Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Apr;10(2):167-9.
doi: 10.1385/ENDO:10:2:167.

The relaxin-like factor is a hormone

E E Büllesbach  1 , R Rhodes, B Rembiesa, C Schwabe
Affiliations

The relaxin-like factor is a hormone

E E Büllesbach et al. Endocrine. 1999 Apr.

Abstract

The relaxin-like factor (RLF) circulates in the bloodstream of humans, interacts with a membrane protein with all the characteristics of ligand-receptor binding, and must therefore be considered a hormone by definition. The polyclonal antibody raised against synthetic human RLF showed no crossreactivity to other structurally related hormones, like insulin and relaxin. The sensitivity of this assay (ED50 at 100 pM) allowed the direct measurement of RLF concentrations in serum. The highest levels were detected in the serum of postpuberty males (190 pM), whereas in females and children, the RLF concentration was one order of magnitude lower.

PubMed Disclaimer

References

    1. J Biol Chem. 1995 Jul 7;270(27):16011-5 - PubMed
    1. Mol Cell Endocrinol. 1996 Aug 9;121(2):171-7 - PubMed
    1. J Clin Endocrinol Metab. 1978 Nov;47(5):1106-10 - PubMed
    1. Endocrinology. 1996 Jul;137(7):3009-13 - PubMed
    1. Genomics. 1994 Mar 1;20(1):13-9 - PubMed

Publication types

LinkOut - more resources