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Mirivadelgat

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Mirivadelgat
Image
Identifiers
  • [2-[4-(cyclopropylmethoxy)-3-[(3-fluoro-4-methoxyphenyl)methylcarbamoyl]phenyl]-3-pyridinyl]methyl (2S)-2-amino-3-methylbutanoate
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC30H34FN3O5
Molar mass535.616 g·mol−1
3D model (JSmol)
  • CC(C)[C@@H](C(=O)OCC1=C(N=CC=C1)C2=CC(=C(C=C2)OCC3CC3)C(=O)NCC4=CC(=C(C=C4)OC)F)N
  • InChI=InChI=1S/C30H34FN3O5/c1-18(2)27(32)30(36)39-17-22-5-4-12-33-28(22)21-9-11-25(38-16-19-6-7-19)23(14-21)29(35)34-15-20-8-10-26(37-3)24(31)13-20/h4-5,8-14,18-19,27H,6-7,15-17,32H2,1-3H3,(H,34,35)/t27-/m0/s1
  • Key:ONYMVJFFLSQCKA-MHZLTWQESA-N

Mirivadelgat is an investigational new drug that is being evaluated by Foresee Pharmaceuticals for the treatment of pulmonary arterial hypertension.[1] It is an aldehyde dehydrogenase 2 activator.[1][2]

References

[edit]
  1. 1 2 "Mirivadelgat". AdisInsight. Springer Nature Switzerland AG. Retrieved 5 July 2026.
  2. Grubwieser P, Bonkat N, Sailer B, Schroll A, Löffler-Ragg J, Weiss G, et al. (April 2026). "Emerging treatments in pulmonary arterial hypertension: a current review". European Journal of Medical Research. 31 887. doi:10.1186/s40001-026-04515-5.